ORC (Organic Rankine Cycle) as a power generation method from medium and low thermal grade heat sources is currently a strong player in the market. Unprecedented energy demand, more environmentallyconcerns and abundant low-grade heat have motivated great actions for ORC usage. In this study, various fields which ORC can cost and technically effectively be applied is introduced and especially waste heat recovery in Ceramics industry evaluated and relevant options suggested and an ORC waste heat recovery system for a specific Ceramic industry (ALVAND Tile and Ceramic Industries Co - Qazvin, IRAN) with real data designed and simulated. By considering different applications, classification on produced power range and heat source temperature is implemented. Reasons on how the ORC can cost effectively fit into the systemis presented. Influence of ORC application on cost, thermal and in some cases exergy efficiencies, system payback time, internal rate of return and net present value depending on rival technologies have been studied to support the idea. This study deals withsimulation of an ORC in a ceramic industry for low-grade waste heat recovery.