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В настоящей работе обобщаются современные данные о биологических функциях и механизмах, обеспечивающих вовлеченность lncRNA PANDAR в процессы развития опухоли, проводится исследование уровня экспрессии lncRNA PANDAR в различных образцах глиомы и опухолевых клеточных линиях, разрабатывается стратегия изучения роли lncRNA PANDAR в глиоме человека.
In this paper the current data on the biological functions and mechanisms that ensure the involvement of lncRNA PANDAR in the processes of tumorigenesis was summarized, the expression levels of lncRNA PANDAR in various samples of glioma and tumor cell lines were studied and the strategy to study the role of lncRNA PANDAR in human glioma was developed.
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