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Title: Mass Spectrometry in Biopharmaceutical Analysis
Creators: Kaltashov Igor A.,
Other creators: Wang Guanbo; Wang Shunhai
Collection: Электронные книги зарубежных издательств; Общая коллекция
Subjects: Biopharmaceutics.; Biopharmaceutics; Biochemische Analyse.; Massenspektrometrie.; Spektroskopie.; Strukturanalyse.; Biopharmacie.; SCIENCE / Chemistry / General.; Biochemical Analysis.; Mass Spectroscopy.; Spectroscopy.; Structural Analysis.; EBSCO eBooks
Document type: Other
File type: PDF
Language: English
Rights: Доступ по паролю из сети Интернет (чтение, печать, копирование)
Record key: on1286807402

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Biopharmaceuticals are a unique class of compounds due to their extreme structural complexity. The current text puts together a variety of the state-of-the art approaches that use mass spectrometry to evaluate various aspects of biopharmaceutical products ranging from monitoring stress-related structural changes to their quantitation in pharmacokinetic studies.

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Table of Contents

  • Preface
  • Contents
  • Chapter 1 Analytical chemistry in biopharma
  • Chapter 2 A brief overview of biological mass spectrometry: concepts and definitions
  • Chapter 3 Characterization of covalent structure of protein therapeutics
  • Chapter 4 Characterization of higher order structure and protein interactions
  • Chapter 5 Biosimilars and comparability studies
  • Chapter 6 Characterization of impurities in biopharmaceutical products
  • Chapter 7 Quantitation of protein therapeutics in biological samples
  • Chapter 8 Non-protein biopharmaceuticals and related macromolecular drugs
  • Chapter 9 What is next?
  • Index

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