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Biopharmaceuticals are a unique class of compounds due to their extreme structural complexity. The current text puts together a variety of the state-of-the art approaches that use mass spectrometry to evaluate various aspects of biopharmaceutical products ranging from monitoring stress-related structural changes to their quantitation in pharmacokinetic studies.
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Table of Contents
- Preface
- Contents
- Chapter 1 Analytical chemistry in biopharma
- Chapter 2 A brief overview of biological mass spectrometry: concepts and definitions
- Chapter 3 Characterization of covalent structure of protein therapeutics
- Chapter 4 Characterization of higher order structure and protein interactions
- Chapter 5 Biosimilars and comparability studies
- Chapter 6 Characterization of impurities in biopharmaceutical products
- Chapter 7 Quantitation of protein therapeutics in biological samples
- Chapter 8 Non-protein biopharmaceuticals and related macromolecular drugs
- Chapter 9 What is next?
- Index
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