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The subject of the graduate qualification work is «Development of recommendations to improve regulations and practices for managing radioactive medical waste in republic of Senegal». For years now we have been facing increased production of waste of all types, but more particularly radioactive waste. Most tertiary care hospitals employ radioisotopes for both diagnostic and therapeutic procedures. Proper disposal of radioactive waste is essential within the broader context of hospital waste management. The primary objective of managing radioactive waste is to ensure that radiation exposure for individuals (including the public, radioactive workers, and patients) and the environment remains within established safety limits. Medical activities using radioactive isotopes for diagnosis, treatment, research and industrialization are the cause. Health establishments play a major role because they are among the major producers of waste and this waste is among the most dangerous, because it carries infectious, chemical, biological or radioactive risks. Continuous monitoring of both the hospital premises and personnel working with radioactive materials is obligatory to evaluate the effectiveness of radiation protection measures. It is essential to maintain records documenting the type and quantity of radioactive waste produced, along with details regarding its management processes. Adequate infrastructure and staffing are necessary to ensure that radiation levels in the environment remain within acceptable safety parameters. Despite the insufficiency of technical services dedicated to waste management within health establishments, the current management system has certain shortcomings. The main constraints identified include: the absence of internal management plans or procedures, the lack of reliable data the volume of waste generated, inadequate funding designated for medical waste management, particularly for radioactive waste, and the absence of capacity-building initiatives for healthcare staff in radioactive waste management. Hence, recognizing the diverse risks and impacts that such waste can pose to both the environment and public health, initiatives have arisen to mitigate these challenges.  Therefore, the implementation of a nationwide strategy for the handling of medical waste, with a specific focus on radioactive waste, in Senegal demonstrates the need to face the challenges of managing the latter. The management of radioactive waste in public sectors adheres to the regulations set forth by the International Atomic Energy Agency. This work is a study aimed at questioning the mechanisms regarding the management of medical waste within public health centers in Senegal, by studying the case of the General Idrissa POUYE hospital (HOGIP). To achieve this objective, we make crucial recommendations for regulation on the subject and improved management practices in health centers in Senegal through the work carried out in relation to the issue.