Details

This work addresses the urgent need for accurate, non-invasive blood flow monitoring by designing and validating a novel speckle correlation optical sensor. Through comparative analysis of traditional blood flow velocity measurement methods — such as Doppler ultrasound and thermodilution — we identified limitations including invasiveness, cost constraints, and depth-resolution trade-offs. Consequently, the speckle correlation method was selected for development, leading to the design and implementation of experimental apparatus. The sensor leverages principles of dynamic laser speckle physics, quantifying microvascular flow velocity by analyzing spatiotemporal correlation decay in coherent light scattered by moving erythrocytes.

• CONTENTS
• INTRODUCTION
• CHAPTER.1 BLOOD FLOW VELOCITY
  • 1.1 The definition of blood flow velocity and its
    • 1.1.1 Physiological Basis and Definition
    • 1.1.2. Vessel Types and Velocity Characteristics
    • 1.1.3 Stratified Flow Phenomenon and Velocity Dist
  • 1.2 Methods for Measuring Blood Flow Velocity
    • 1.2.1 Doppler Ultrasound
    • 1.2.2 Laser Doppler Flowmetry
    • 1.2.3 Thermodilution Method
    • 1.2.4 Optical Coherence Tomography Angiography
    • 1.2.5 Photoacoustic Imaging (PAI) 
    • 1.2.6 Laser speckle contrast analysis (LASCA)
• CHAPTER.2 BASICS OF SPECKLE CORRELATION SENSOR FOR
  • 2.1 Theoretical basis
  • 2.2 Equipment
  • 2.3 Process
  • 2.4 Summary
• CHAPTER.3 DEVELOPMENT AND DATA ANALYSIS OF SPECKLE
  • 3.1 Measurements setup and selection
  • 3.2 Experimental data and data analysis
• CONCLUSION
• REFERENCES